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Idiosyncratic DILI (IDILI) is unpredictable, not dose-dependent, and may take weeks or months to develop
Obesity, insulin resistance, diabetes and cardiovascular risk in children: an American Heart Association scientific statement from the Atherosclerosis, Hypertension and Obesity in the Young Committee (Council on Cardiovascular Disease in the Young) and the Diabetes Committee (Council on Nutrition, Physical Activity and Metabolism)
Protein carbonyl, a product of protein oxidative damage, has also been shown to be decreased by riboflavin administration in the rat models of diabetes (Reference Alam, Iqbal and Naseem31) , renal toxicity (Reference Alhazza, Hassan and Ebaid23) and anticancer drug-induced toxicities (Reference Naseem, Hassan and Alhazza28) , while its elevated level has been reported in riboflavin-deficient fishes (Reference Jiang, Chen and Liu33,Reference Chen, Feng and Jiang34)
Antioxidants (Basel) 2022;11:1282
Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer
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